Decoys 2: The Second Seduction (2007)

Nice guy Sam is convinced by his roommates to join in the big  contest to see who can score with the most girls by the end of the semester. Sam is really only interested in one girl. But she's his  best friend, and you know how that goes.

Luke, our survivor from the first film and is now a teaching assistant and working on finishing his degree.  He's seeing a psychiatrist to try to get over the death of his best friend and the previous alien breeding experiences at his last college.

When he sees Constance, an alien lady from the first film who's masquerading as a PhD at the college, he understandably freaks, but no one will believe anything he says. And why would they? He says she's an alien with tentacles who kills guys by sleeping with them.

With the dorm challenge to sleep with as many girls as possible, it's only a matter of time before guys start dying... because they've slept with an alien who needs their body as a host for breeding, but there are issues with that so the sex usually ends up accidentally killing them.

Luke finally finds an ally in Sam, who has started to become suspicious of strange goings on on campus.  It's the same basic premise as the first one, except there's no alien-human romance, just heartless aliens trying to fill our human males with their eggs.